logo

KOALA SCIENCE COMMUNITY
     Research, Connect, Protect

 

Search

Literature

Koala Biovar of Chlamydia pneumoniae Infects Human and Koala Monocytes and Induces Increased Uptake of Lipids In Vitro 

KATIE A. COLES,1,2* PETER TIMMS,3 AND DAVID W. SMITH2,4 

Departments of Public Health1 and Microbiology,2 the University of Western Australia, and Western Australian Centre for Pathology and Medical Research, Sir Charles Gairdner Hospital,4 Perth, and Centre for Molecular Biotechnology, School of Life Sciences, Queensland University of Technology, Brisbane,3 Australia 

ABSTRACT

We examined the ability of the koala biovar of Chlamydia pneumoniae to infect both Hep-2 cells and human monocytesandtheeffectofinfectionontheformationoffoamcells.Thekoalabiovarproducedlargeinclusions in both human and koala monocytes and in Hep-2 cells. Koala C. pneumoniae induced foam cell formation with and without added low-density lipoprotein, in contrast to TW183, which produced increased foam cell formation only in the presence of low-density lipoprotein.

 

  • All
  • 2013
  • Biogeography
  • Biology
  • Chlamydia
  • Diet
  • Disease
  • Ecology
  • Ellis
  • Eucalyptus
  • Genetics
  • Habitat
  • Infection
  • Interventions
  • Koala
  • Lunney
  • Threats
  • Timms
load more hold SHIFT key to load all load all