Methaemoglobin Formation in the Koala and the Possum
E. Ogawa 1'2, S. S. O'Callaghan1 ~ and N. S. Agar1
1Department of Physiology, University of New England, Armidale, Australia;
2Department of Veterinary Medicine, Azabu University, Kangawa, Japan
Measurements were made of glutathione (GSH) levels, catalase activity and the oxidant sensitivity of the erythrocytes from the koala (Phascolarctos cinereus) and the common brushtail possum (Trichosurus vulpecula). The oxidant sensitivity was tested by treating the haemolysates with either 0.55 mM H202 or 1.4 mM NaNO2. The erythrocytes of the koala had greater levels of GSH and catalase and yet were found to be more susceptible to oxidation induced by both these oxidants.